abstract：:Over the last decade, biologic therapeutic proteins have advanced the treatment of diseases such as rheumatoid arthritis (RA). Therapeutic antibodies such as infliximab, adalimumab, rituximab, tocilizumab, golimumab, certolizumab pegol, the receptor construct etanercept, and abatacept, an anticluster of differentiatio...

journal_title：Clinical rheumatology

authors： Alawadhi A,Alawneh K,Alzahrani ZA

更新日期：2012-09-01 00:00:00

abstract：:Information about the distribution of effusion within the arthritic knee joint should be considered in selecting an anatomical approach for arthrocentesis. We recorded ultrasound measurements of fluid distribution in the knees of patients attending our clinic for knee injections under ultrasound guidance. In a cross-s...

journal_title：Clinical rheumatology

authors： Hirsch G,O'Neill T,Kitas G,Klocke R

更新日期：2012-08-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent self-limited attacks of fever and polyserositis. Reactive amyloid A amyloidosis is the most devastating complication of FMF, and amyloidosis continues to occur in the colchicine era in untreated and noncompliant patients. U...

journal_title：Clinical rheumatology

authors： Özçakar ZB,Yüksel S,Ekim M,Yalçınkaya F

更新日期：2012-08-01 00:00:00

abstract：:Pauci-immune necrotizing glomerulonephritis is a form of a rapidly progressive glomerulonephritis that is associated with the anti-neutrophil cytoplasmic antibodies (ANCA). ANCA-associated pauci-immune glomerulonephritis may be secondary to rheumatic diseases. We report on a patient with limited cutaneous systemic scl...

journal_title：Clinical rheumatology

authors： Chan PT,Mok CC

更新日期：2012-08-01 00:00:00

abstract：:This study was designed to explore the profile of immune cell subsets, including T, B, natural killer (NK), and NKT cells, in systemic lupus erythematosus (SLE) patients, and to determine their relationships with the clinical index and the effects of cyclophosphamide (CYC) and mycophenolate mofetil (MMF) treatment. SL...

journal_title：Clinical rheumatology

authors： Zhao L,Jiang Z,Jiang Y,Ma N,Wang K,Zhang Y

更新日期：2012-06-01 00:00:00

abstract：:Clinical guidelines regarding anti-viral prophylaxis for HBV surface antigen (HBsAg) carriers starting anti-TNFα agents are not yet fully established, even in endemic regions of HBV infection. We retrospectively collected the clinical data of 52 HBsAg carriers with rheumatoid arthritis (RA) or ankylosing spondylitis (...

journal_title：Clinical rheumatology

authors： Ryu HH,Lee EY,Shin K,Choi IA,Lee YJ,Yoo B,Park MC,Park YB,Bae SC,Yoo WH,Kim SI,Lee EB,Song YW

更新日期：2012-06-01 00:00:00

abstract：:Anti-CCP (cyclic citrullinated peptide) is considered the most useful laboratory tool in the diagnosis of rheumatoid arthritis (RA). Some authors have also found this autoantibody in patients with scleroderma (SSc). The study aimed to investigate the prevalence of anti-CCP antibodies in SSc patients from Southern Braz...

journal_title：Clinical rheumatology

authors： Polimeni M,Feniman D,Skare TS,Nisihara RM

更新日期：2012-05-01 00:00:00

abstract：:Biological agents, particularly anti-Tumour Necrosis Factor (TNF)-α agents, have emerged as an effective treatment in patients with chronic inflammatory diseases. An association between anti-TNF-α antibodies and reactivation of latent tuberculosis infection (LTBI) has been established. Appropriate screening for TB inf...

journal_title：Clinical rheumatology

authors： Mínguez S,Latorre I,Mateo L,Lacoma A,Diaz J,Olivé A,Domínguez J

更新日期：2012-05-01 00:00:00

abstract：:Cytokine gene loci are one of the potential susceptibility factors in immuno-inflammatory diseases. Interleukin1 (IL-1) is a major monocyte derived proinflammatory cytokine that mediates tissue damage and cartilage loss in chronic arthritis. IL-1 locus has been linked to various autoimmune diseases, but data on juveni...

journal_title：Clinical rheumatology

authors： Aggarwal A,Srivastava R,Singh S,Kumar Dubey P

更新日期：2012-04-01 00:00:00

abstract：:The clinical response to traditional disease-modifying anti-rheumatic drugs (DMARDs) in indigent South Africans with early rheumatoid arthritis was investigated. A cohort of patients with early (≤2 years) RA who were DMARD-naïve at inception were prospectively assessed for response to DMARDs using the Simplified Disea...

journal_title：Clinical rheumatology

authors： Hodkinson B,Musenge E,Ally M,Meyer PW,Anderson R,Tikly M

更新日期：2012-04-01 00:00:00

abstract：:This study was designed to investigate the functional heterogeneity of human Th17 and how their plasticity shapes the nature of immune cell responses to inflammation and autoimmune diseases, such as systemic lupus erythematosus (SLE). We evaluated functional Th17 cell subsets based on the profile of cytokine productio...

journal_title：Clinical rheumatology

authors： Henriques A,Inês L,Pais ML,da Silva JA,Paiva AA

更新日期：2012-03-01 00:00:00

abstract：:Joint lavage for knee osteoarthritis is an invasive procedure that can be stressful and painful. We aimed to assess the impact of music therapy on perioperative anxiety, pain and tolerability of the procedure in patients undergoing joint lavage performed with two needles. We randomized all patients diagnosed with knee...

journal_title：Clinical rheumatology

authors： Ottaviani S,Bernard JL,Bardin T,Richette P

更新日期：2012-03-01 00:00:00

abstract：:The objective of this study was to analyze the clinical, laboratorial, and therapeutical response of polymyalgia rheumatica (PMR) to anti-tumor necrosis factor (anti-TNF) treatment. We systematically searched English articles on the subjects of PMR who were treated with TNF blockers in Pubmed from 1994 to 2010. In add...

journal_title：Clinical rheumatology

authors： Aikawa NE,Pereira RM,Lage L,Bonfá E,Carvalho JF

更新日期：2012-03-01 00:00:00

abstract：:This study aimed to compare the intraobserver and interobserver reliability of three-dimensional (3D) and two-dimensional (2D) power Doppler ultrasonography (PDUS) and to assess the relationship between 3D PDUS and clinical parameters in patients with rheumatoid arthritis (RA). Bilateral second/third metacarpophalange...

journal_title：Clinical rheumatology

authors： Watanabe T,Takemura M,Sato M,Sekine A,Fukuoka D,Seishima M,Shimizu K,Matsuoka T

更新日期：2012-02-01 00:00:00

abstract：:Atherosclerosis has been shown to be increased in chronic inflammatory diseases including ankylosing spondylitis (AS). Impaired endothelial function, the first step in atherosclerosis, may be reflected by changes in various endothelial biomarkers of hemostasis and the release of several cellular adhesion molecules or ...

journal_title：Clinical rheumatology

authors： Taylan A,Sari I,Kozaci DL,Yildiz Y,Bilge S,Coker I,Maltas S,Gunay N,Akkoc N

更新日期：2012-01-01 00:00:00

abstract：:Systemic sclerosis (SSc) is complicated by pulmonary hypertension and right ventricle (RV) failure in approximately 10% of the patients. Factors influencing the reactivity of pulmonary circulation to vasodilators are not established, while the examination of vasoreactivity is important in determining the treatment, be...

journal_title：Clinical rheumatology

authors： Plazak W,Gryga K,Sznajd J,Wilisowska J,Czarnobilska E,Goncerz G,Podolec P,Musial J

更新日期：2012-01-01 00:00:00

abstract：:The objective of this work was to study the clinical and serological profiles of rheumatoid arthritis in Burkina Faso (West Africa). It is a cross-sectional study conducted from March 2006 to February 2009 in the Internal Medicine Department of the University Hospital Yalgado Ouedraogo. All patients seen in the rheuma...

journal_title：Clinical rheumatology

authors： Ouédraogo DD,Singbo J,Diallo O,Sawadogo SA,Tiéno H,Drabo YJ

更新日期：2011-12-01 00:00:00

abstract：:Despite the proven health benefits, patients with rheumatoid arthritis (RA) are found to be less physically active than their healthy peers. The aim of this study was to examine to what extent and how physical activity, defined as any bodily movement resulting in energy expenditure, is currently promoted by health car...

journal_title：Clinical rheumatology

authors： Hurkmans EJ,de Gucht V,Maes S,Peeters AJ,Ronday HK,Vliet Vlieland TP

更新日期：2011-12-01 00:00:00

abstract：:This study aims to measure the frequency of medication error (ME) in rheumatology outpatients of the Social Security System (SS) in Mexico and to measure the costs by comparing the days lost at work as direct consequence of the medication error against the theoretical cost of no error in the process. A prospective 6-m...

journal_title：Clinical rheumatology

authors： Aceves-Avila FJ,Benites-Godínez V,Ramos-Remus C

更新日期：2011-11-01 00:00:00

abstract：:Initial treatment of trapeziometacarpal osteoarthritis (TMO) often consists of intra-articular injection of corticosteroids or hyaluronic acid. Several studies have shown that ultrasound (US)-guided injections demonstrate greater precision and effectiveness when compared to blind techniques. The aim of our study was t...

journal_title：Clinical rheumatology

authors： Di Sante L,Cacchio A,Scettri P,Paoloni M,Ioppolo F,Santilli V

更新日期：2011-09-01 00:00:00

abstract：:Sarcoidosis is a multisystemic disease with cutaneous lesions present in about one fourth of patients. Cutaneous lesions may be specific or nonspecific based on the presence or the absence of sarcoidal granulomas. Subcutaneos sarcoidosis is the less frequent of the specific cutaneous lesions of sarcoidosis. We report ...

journal_title：Clinical rheumatology

authors： Dalle Vedove C,Colato C,Girolomoni G

更新日期：2011-08-01 00:00:00

abstract：:A cohort of patients with recently diagnosed axial spondyloarthritis (SpA) was characterized with emphasis on gender differences and factors leading to delay in diagnosis. Clinical, laboratory, and imaging data of 151 consecutive patients diagnosed with ankylosing spondylitis or undifferentiated SpA in 2004-2009 and s...

journal_title：Clinical rheumatology

authors： Slobodin G,Reyhan I,Avshovich N,Balbir-Gurman A,Boulman N,Elias M,Feld J,Mader R,Markovitz D,Rimar D,Rosner I,Rozenbaum M,Zisman D,Odeh M

更新日期：2011-08-01 00:00:00

abstract：:This study aims to explore the effectiveness of low dose of etanercept (ETN) in patients with ankylosing spondylitis (AS) who achieve a good control of their disease in daily clinical practice. This is a case series of AS patients treated with ETN. According to the judgment of the treating rheumatologist and patient's...

journal_title：Clinical rheumatology

authors： Navarro-Compán V,Moreira V,Ariza-Ariza R,Hernández-Cruz B,Vargas-Lebrón C,Navarro-Sarabia F

更新日期：2011-07-01 00:00:00

abstract：:To determine serum interleukin-33 (IL-33) levels and their associations with clinical parameters in patients with systemic sclerosis (SSc). Serum IL-33 levels were examined by enzyme-linked immunosorbent assay in 69 patients with SSc and 30 healthy individuals. In a retrospective longitudinal study, sera from 14 patie...

journal_title：Clinical rheumatology

authors： Yanaba K,Yoshizaki A,Asano Y,Kadono T,Sato S

更新日期：2011-06-01 00:00:00

abstract：:We and others have previously shown that IL-17 is elevated in the synovial fluid of patients with reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) having acute synovitis. Major source for IL-17 is Th17 cells, which differentiate from Th0 cells under the influence of TGF-β and IL-6, IL1-β and are ma...

journal_title：Clinical rheumatology

authors： Singh AK,Misra R,Aggarwal A

更新日期：2011-06-01 00:00:00

abstract：:This study aims to examine the needs and preferences regarding the delivery of health care services and information provision and their determinants in patients with systemic sclerosis (SSc). A questionnaire was sent to 77 SSc outpatients, comprising 27 items on health care needs within the domains physical, psycholog...

journal_title：Clinical rheumatology

authors： Schouffoer AA,Zirkzee EJ,Henquet SM,Caljouw MA,Steup-Beekman GM,van Laar JM,Vlieland TP

更新日期：2011-06-01 00:00:00

abstract：:The burden of anxiety in patients with systemic lupus erythematosus (SLE) compared to those with other inflammatory rheumatological conditions is unclear. We aimed to compare the frequency and level of anxiety between patients with SLE, rheumatoid arthritis (RA), and gout and healthy individuals and explore independen...

journal_title：Clinical rheumatology

authors： Mak A,Tang CS,Chan MF,Cheak AA,Ho RC

更新日期：2011-06-01 00:00:00

abstract：:To present the clinical and pathological findings in patients presenting with myositis caused by syphilis. The literature is reviewed, and pathophysiologic factors discussed. A 49-year-old Caucasian heterosexual male with a known history of stable human immunodeficiency virus (HIV) and hepatitis C (HCV) co-infection, ...

journal_title：Clinical rheumatology

authors： Yacyshyn E,Chiowchanwisawakit P,Emery DJ,Jhamandas J,Resch L,Taylor G

更新日期：2011-05-01 00:00:00

abstract：:In patients with fibromyalgia (FM) syndrome, stress and pain may chronically enhance sympathetic activity, altering cardiovascular response and inducing endothelial dysfunction. We investigated endothelial function in FM patients using echocardiography and analyzed whether endothelial function was affected by the clin...

journal_title：Clinical rheumatology

authors： Cho KI,Lee JH,Kim SM,Lee HG,Kim TI

更新日期：2011-05-01 00:00:00

abstract：:Disease-modifying antirheumatic biological and non-biological therapies are associated with reduced disease progression and joint destruction. Suggestions have been made that total knee and hip joint arthroplasty indications are decreasing as a beneficial effect of the new forms of therapy for rheumatoid arthritis. We...

journal_title：Clinical rheumatology

authors： De Piano LP,Golmia RP,Scheinberg MA

更新日期：2011-04-01 00:00:00

abstract：:Biologic therapies have brought improved efficacy in the field of rheumatoid arthritis (RA), but their use in clinical practice may be limited by concerns over cost. Predictive models are, therefore, needed to identify those people with RA with the worst potential outcomes, who will benefit most from the use of these ...

journal_title：Clinical rheumatology

authors： Conaghan PG

更新日期：2011-03-01 00:00:00

abstract：:The Revised Fibromyalgia Impact Questionnaire (FIQR) attempts to address the limitations of the Fibromyalgia Impact Questionnaire (FIQ). As there is no Turkish version of the FIQR available, we aimed to investigate the validity and reliability of a Turkish translation of the FIQR in Turkish female fibromyalgia (FM) pa...

journal_title：Clinical rheumatology

authors： Ediz L,Hiz O,Toprak M,Tekeoglu I,Ercan S

更新日期：2011-03-01 00:00:00

abstract：:This study aims to determine the prevalence and clinical significance of anti-CCP isotype IgA in a population of patients with primary Sjögren's syndrome (pSS). Sixty-two patients diagnosed according to the USA-European classification criteria for pSS were examined two to four times during a 60.4-month follow-up, and ...

journal_title：Clinical rheumatology

authors： Haga HJ,Andersen DT,Peen E

更新日期：2011-03-01 00:00:00

abstract：:Children with juvenile idiopathic arthritis (JIA) may infrequently present with localized anterior knee pain or swelling, in addition to generalize knee pain induced by JIA. We report five cases of deep infrapatellar bursitis in children with JIA. The clinical features, radiological findings, management, and outcome o...

journal_title：Clinical rheumatology

authors： Alqanatish JT,Petty RE,Houghton KM,Guzman J,Tucker LB,Cabral DA,Cairns RA

更新日期：2011-02-01 00:00:00

abstract：:Juvenile systemic lupus erythematosus is a rare multisystemic autoimmune disease with variable clinical manifestations, and disease onset before 16 years of age. Patients younger than 5 years are rarely affected and the age of onset may contribute to the course of disease in terms of clinical presentation, organ invol...

journal_title：Clinical rheumatology

authors： Hedrich CM,Zappel H,Straub S,Laass MW,Wieczorek K,Hahn G,Heubner G,Gahr M

更新日期：2011-02-01 00:00:00

abstract：:Over the last few years, several studies in patients with systemic lupus erythematosus (SLE) have demonstrated an association between valvulopathy, including Libman-Sacks endocarditis (LS) and the presence of antiphospholipid antibodies (aPL), suggesting a role of these antibodies in the pathogenesis of the lesions. O...

journal_title：Clinical rheumatology

authors： Mattos P,Santiago MB

更新日期：2011-02-01 00:00:00

abstract：:The aim of this study is to assess the gender differences in spondyloarthritides (SpAs) in terms of disease onset, clinical presentation, and the Bath Ankylosing Spondylitis Disease Activity and Functional indices (BASDAI and BASFI). We analysed data from a predominantly female cohort. Five hundred and 16 patients (ma...

journal_title：Clinical rheumatology

authors： Roussou E,Sultana S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Clustering of autoimmune diseases is common and may be due to genetic background and exposition to environmental triggers. OBJECTIVE:The aim is to carry out a laboratory and clinical study of the prevalence of gastrointestinal organ-specific autoantibodies in rheumatoid arthritis (RA) patients and their rel...

journal_title：Clinical rheumatology

authors： Goeldner I,Skare TL,de Messias Reason IT,Nisihara RM,Silva MB,da Rosa Utiyama SR

更新日期：2011-01-01 00:00:00

abstract：:Chronic hepatitis C virus (HCV) viremia has been known to provoke a plethora of autoimmune syndromes referred to as extrahepatic manifestations of chronic HCV infection. Aim of the current study was to assess the prevalence of rheumatologic manifestations among Egyptians with hepatitis C infection and its' association...

journal_title：Clinical rheumatology

authors： Mohammed RH,ElMakhzangy HI,Gamal A,Mekky F,El Kassas M,Mohammed N,Abdel Hamid M,Esmat G

更新日期：2010-12-01 00:00:00

abstract：:The objectives of the study were to investigate short and long-term changes and relations to treatment response of plasma interleukin-6 (IL-6), vascular endothelial growth factor (VEGF), YKL-40, matrix metalloproteinase-3 (MMP-3), and total aggrecan in patients with spondyloarthritis (SpA) treated with tumor necrosis ...

journal_title：Clinical rheumatology

authors： Pedersen SJ,Hetland ML,Sørensen IJ,Ostergaard M,Nielsen HJ,Johansen JS

更新日期：2010-11-01 00:00:00